SIGNOR 3.0

Homo sapiens

SIGNOR is a repository of manually annotated causal relationships between human proteins, chemicals of biological relevance, stimuli and phenotypes. The search field below allows users to access the entity page detailing all the causal relationships annotated to the query entity. SIGNOR also curates pathways that can be accessed by making choices in the drop down menu below. In addition SIGNOR offers advanced graph tools to explore the human cell network.

This tool draws networks connecting genes that have been associated to different diseases. The user can select within three different disease gene lists using the radio button below. The resulting connection-graphs can be displayed at three level of complexity. Level 1 (connect): only direct interactions between disease genes are shown. Level 2 (Add bridge proteins) disease genes that connect via bridge proteins are also shown. Level 3 (all): all the interactions of the disease genes annotated in SIGNOR are shown.

Advanced Relation Search

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Regulator(s) Target(s)
Mechanism	Effect
Organism	Tissue
Cell	System
Direct

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The SIGnaling Network
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Advanced Relation Search

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