Summary

Name TMEM129
Full Name E3 ubiquitin-protein ligase TM129
Synonyms RING-type E3 ubiquitin transferase TM129 |
Primary ID A0AVI4
Links - -
Type protein
Relations 1
Function E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2. Exploited by viral US11 proteins to mediate HLA class I proteins degradation.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination TMEM129 0.2
Publications: 1 Organism: Homo Sapiens