+ |
alvimopan | down-regulates activity
chemical inhibition
|
OPRD1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-257772 |
|
|
in vitro |
|
pmid |
sentence |
18313920 |
A series of N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines, l opioid receptor antagonists, analogs of alvimopan, were prepared using solid phase methodology. This study led to the identification of a highly selective l opioid receptor antagonist, which interacts selectively with l peripheral receptors. |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
alvimopan | down-regulates activity
chemical inhibition
|
OPRK1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-257774 |
|
|
in vitro |
|
pmid |
sentence |
18313920 |
A series of N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines, l opioid receptor antagonists, analogs of alvimopan, were prepared using solid phase methodology. This study led to the identification of a highly selective l opioid receptor antagonist, which interacts selectively with l peripheral receptors. |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
alvimopan | down-regulates activity
chemical inhibition
|
OPRM1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-257773 |
|
|
in vitro |
|
pmid |
sentence |
18313920 |
A series of N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines, l opioid receptor antagonists, analogs of alvimopan, were prepared using solid phase methodology. This study led to the identification of a highly selective l opioid receptor antagonist, which interacts selectively with l peripheral receptors. |
|
Publications: |
1 |
Organism: |
In Vitro |