| + |
TK2 | down-regulates quantity 
chemical modification
|
2'-deoxycytidine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280580 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25215937 |
Thymidine kinase 2 (TK2, EC 27.1.21) catalyzes the transfer of the γ-phosphate group from ATP to the 5′-hydroxyl group of thymidine (dT), deoxycytidine (dC), or deoxyuridine (dU) to form their corresponding monophosphates. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
2'-deoxycytidine | up-regulates quantity 
precursor of
|
2'-deoxycytosine 5'-monophosphate(2-) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280582 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25215937 |
Thymidine kinase 2 (TK2, EC 27.1.21) catalyzes the transfer of the γ-phosphate group from ATP to the 5′-hydroxyl group of thymidine (dT), deoxycytidine (dC), or deoxyuridine (dU) to form their corresponding monophosphates. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280568 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20637175 |
Human deoxycytidine kinase (dCK4; EC 2.7.1.74) catalyzes the phosphorylation of 2′-deoxycytidine (dCyd), 2′-deoxyadenosine and 2′-deoxyguanosine to their corresponding monophosphate forms, using ATP or UTP as phosphoryl donors. This reaction is the first and rate-limiting step of the deoxyribonucleoside salvage pathway, which provides deoxynucleoside triphosphates for DNA replication and repair as an alternative to de novo nucleotide synthesis |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275810 |
|
|
|
|
| pmid |
sentence |
| 20637175 |
Human deoxycytidine kinase (dCK4; EC 2.7.1.74) catalyzes the phosphorylation of 2′-deoxycytidine (dCyd), 2′-deoxyadenosine and 2′-deoxyguanosine to their corresponding monophosphate forms, using ATP or UTP as phosphoryl donors. This reaction is the first and rate-limiting step of the deoxyribonucleoside salvage pathway, which provides deoxynucleoside triphosphates for DNA replication and repair as an alternative to de novo nucleotide synthesis |
|
| Publications: |
3 |
Organism: |
Homo Sapiens, |
| + |
DCK | down-regulates quantity
chemical modification
|
2'-deoxycytidine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280566 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20637175 |
Human deoxycytidine kinase (dCK4; EC 2.7.1.74) catalyzes the phosphorylation of 2′-deoxycytidine (dCyd), 2′-deoxyadenosine and 2′-deoxyguanosine to their corresponding monophosphate forms, using ATP or UTP as phosphoryl donors. This reaction is the first and rate-limiting step of the deoxyribonucleoside salvage pathway, which provides deoxynucleoside triphosphates for DNA replication and repair as an alternative to de novo nucleotide synthesis |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
2'-deoxycytidine