4.0
Summary
| Name |  acalabrutinib
|
| Synonyms | (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide (ChEBI), 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-(2-pyridyl)benzamide (ChEBI), acalabrutinib (WHO MedNet), acalabrutinib (WHO MedNet), acalabrutinib (WHO MedNet), acalabrutinibum (WHO MedNet), ACP-196 (ChemIDplus), Calquence (ChemIDplus) |
| IUPAC | 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide |
| Formula | C26H23N7O2 |
| PRIMARY ID (Read more) |
CHEBI:167707 |
| Type | chemical |
| Relations | 1 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | acalabrutinib | down-regulates activity 
chemical inhibition
|
BTK | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |