Relation Results

Summary

Name desloratadine
Synonyms 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (ChEMBL), 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine (ChemIDplus), descarboethoxyloratadine (ChemIDplus), DESLORATADINE (ChEMBL), desloratadine (KEGG DRUG)
IUPAC 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Formula C19H19ClN2
PRIMARY ID
(Read more)		 CHEBI:291342
Type chemical
Relations 1

Viewer

Type: Score: Layout: SPV 
0.8desloratadineHRH1

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ desloratadinedown-regulates activity img/direct_inhibition.png chemical inhibition HRH1 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-257784 Homo sapiens U-373MG Cell
pmid sentence
We therefore tested how receptor internalization influenced the binding properties of a variety of H1-receptor antagonists. In this report, we present our findings that there were clear differences between the effect of histamineinduced H1-receptor internalization on the inhibition of [ 3 H]mepyramine binding by sedative and non-sedative H1-receptor antagonists in intact cells
Publications: 1 Organism: Homo Sapiens
a simple tooltip