4.0
Summary
| Name |  methotrexate
|
| Synonyms | 4-amino-10-methylfolic acid (ChemIDplus), 4-amino-N(10)-methylpteroylglutamic acid (NIST Chemistry WebBook), Emtexate (DrugBank), Ledertrexate (DrugBank), Methotrexate (KEGG COMPOUND), METHOTREXATE (PDBeChem), methotrexate (KEGG DRUG), methotrexatum (ChemIDplus), metotrexato (ChemIDplus), MTX (ChemIDplus), N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid (NIST Chemistry WebBook), Rheumatrex (DrugBank), Trexall (DrugBank) |
| IUPAC | N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid |
| Formula | C20H22N8O5 |
| PRIMARY ID (Read more) |
CHEBI:44185 |
| Type | chemical |
| Relations | 1 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | methotrexate | down-regulates activity 
chemical inhibition
|
DHFR | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |