| + |
episterol ester | up-regulates activity 
chemical activation
|
CNR1 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264266 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29751000 |
2-AG is an endocannabinoid that activates the cannabinoid CB1 receptor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Brain |
| + |
PTGS2 | down-regulates quantity 
chemical modification
|
episterol ester |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264270 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19126760 |
After biosynthesis, 2-AG is partially degraded by postsynaptic COX-2, and partly released to the extracellular space.  |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DAGLB | up-regulates quantity
chemical modification
|
episterol ester |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264265 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 26787883 |
Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
episterol ester