| + |
ACADL | up-regulates quantity 
chemical modification
|
trans-dodec-2-enoyl-CoA(4-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280342 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18227065 |
Very-long-chain acyl-CoA dehydrogenase (VLCAD) is a member of the family of acyl-CoA dehydrogenases (ACADs). Very-long-chain acyl-CoA dehydrogenase (VLCAD)3 is one of five acyl-CoA dehydrogenases (ACADs) that catalyze the initial, rate-limiting step of mitochondrial fatty acid β-oxidation, with distinct but overlapping fatty acyl chain-length specificities.When myristoyl-CoA was added, the yellow enzyme solution turned colorless, indicating that the enzyme flavin was reduced by the substrate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
lauroyl-CoA(4-) | up-regulates quantity
precursor of
|
trans-dodec-2-enoyl-CoA(4-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280343 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18227065 |
Very-long-chain acyl-CoA dehydrogenase (VLCAD) is a member of the family of acyl-CoA dehydrogenases (ACADs). Very-long-chain acyl-CoA dehydrogenase (VLCAD)3 is one of five acyl-CoA dehydrogenases (ACADs) that catalyze the initial, rate-limiting step of mitochondrial fatty acid β-oxidation, with distinct but overlapping fatty acyl chain-length specificities.When myristoyl-CoA was added, the yellow enzyme solution turned colorless, indicating that the enzyme flavin was reduced by the substrate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ECHS1 | down-regulates quantity 
chemical modification
|
trans-dodec-2-enoyl-CoA(4-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280344 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 40804397 |
The ECHS1 (short-chain enoyl-CoA hydratase 1) gene is critical for mitochondrial fatty acid β-oxidation and branched-chain amino acid metabolism. In particular, enzymatic assays and molecular characterization from the late 20th to early 21st century confirmed that ECHS1 catalyzes the hydration of short-chain enoyl-CoA, a key step in mitochondrial β-oxidation, essential for metabolic stability. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
trans-dodec-2-enoyl-CoA(4-) | up-regulates quantity
precursor of
|
(S)-3-hydroxylauroyl-CoA |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280347 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 40804397 |
The ECHS1 (short-chain enoyl-CoA hydratase 1) gene is critical for mitochondrial fatty acid β-oxidation and branched-chain amino acid metabolism. In particular, enzymatic assays and molecular characterization from the late 20th to early 21st century confirmed that ECHS1 catalyzes the hydration of short-chain enoyl-CoA, a key step in mitochondrial β-oxidation, essential for metabolic stability. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
trans-dodec-2-enoyl-CoA(4-)