Relation Results

Summary

Name mepyramine
Synonyms Mepyramine (KEGG COMPOUND), N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine (NIST Chemistry WebBook), N-(p-methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine (NIST Chemistry WebBook), N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine (NIST Chemistry WebBook), pyranisamine (ChemIDplus), Pyrilamine (KEGG COMPOUND)
IUPAC
Formula
PRIMARY ID
(Read more)		 CHEBI:6762
Type chemical
Relations 1

Viewer

Type: Score: Layout: SPV 
0.8mepyramineHRH1

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Relations
Regulator
Mechanism
target
score ℹ
+ mepyraminedown-regulates activity img/direct_inhibition.png chemical inhibition HRH1 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258748 Cricetulus griseus CHO Cell
pmid sentence
The human H1-receptor cDNA was transfected into Chinese hamster ovary cells (CHO) via an eukaryotic expression vector; the receptor protein present on cell membranes specifically bound [3H]mepyramine with a Kd of 3.7 nM. The binding was displaced by H1-histamine-receptor antagonists and histamine. Affinity of histamine and selected histamine antagonists for human H, receptors expressed in CHO cells (CHO H,-30) and a comparison with HI receptors found in guinea pig cerebellum.
Publications: 1 Organism: Cricetulus Griseus
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