Summary

Name pralatrexate
Synonyms (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid (ChemIDplus), (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid (IUPAC), 10-Propargyl-10-deazaaminopterin (KEGG DRUG), Folotyn (ChemIDplus), HSDB 7786 (ChemIDplus), N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid (ChemIDplus), pralatrexate (WHO MedNet), pralatrexate (KEGG DRUG), pralatrexato (WHO MedNet), pralatrexatum (WHO MedNet)
IUPAC N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid
Formula C23H23N7O5
PRIMARY ID
(Read more)		 CHEBI:71223
Type chemical
Relations 3

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Relations

Regulator Mechanism target score ℹ
+ pralatrexatedown-regulates activity img/direct_inhibition.png chemical inhibition DHFR 0.8
Publications: 2 Organism: Homo Sapiens
+ pralatrexatedown-regulates activity img/direct_inhibition.png chemical inhibition TYMS 0.8
Publications: 1 Organism: Homo Sapiens