Summary

Name selumetinib
Synonyms ARRY 142886 (ChemIDplus), ARRY-142886 (ChemIDplus), ARRY142886 (ChEBI), AZD 6244 (ChemIDplus), AZD-6244 (ChEBI), AZD6244 (ChemIDplus), selumetinib (WHO MedNet), selumetinib (WHO MedNet), selumetinib (WHO MedNet), selumetinibum (WHO MedNet)
IUPAC 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
Formula C17H15BrClFN4O3
PRIMARY ID
(Read more)		 CHEBI:90227
Type chemical
Relations 5
Pathways SARS-CoV MAPK PERTURBATION

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Relations

Regulator Mechanism target score ℹ
+ selumetinibdown-regulates img/direct_inhibition.png chemical inhibition MEK1/2 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:SARS-CoV MAPK PERTURBATION
+ selumetinibdown-regulates activity img/direct_inhibition.png chemical inhibition ERK1/2 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:SARS-CoV MAPK PERTURBATION
+ selumetinibdown-regulates activity img/direct_inhibition.png chemical inhibition MAP2K1 0.8
Publications: 1 Organism: In Vitro
+ selumetinibdown-regulates img/direct_inhibition.png chemical inhibition MAP2K1 0.8
Publications: 1 Organism: Homo Sapiens
+ selumetinibdown-regulates activity img/direct_inhibition.png chemical inhibition MAP2K2 0.8
Publications: 1 Organism: In Vitro