Relation Results

Summary

Name vatalanib
Synonyms CGP 79787 (ChemIDplus), CGP-79787 (ChemIDplus), CGP79787 (ChEBI), N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (ChemIDplus), N-(p-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine (ChEBI), PTK 787 (ChEBI), PTK-787 (ChEBI), PTK/ZK (ChEBI), PTK787 (ChEBI), vatalanib (WHO MedNet), vatalanib (WHO MedNet), vatalanib (WHO MedNet), vatalanib (WHO MedNet), ZK-232934 (ChemIDplus)
IUPAC N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
Formula C20H15ClN4
PRIMARY ID
(Read more)		 CHEBI:90620
Type chemical
Relations 4

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Type: Score: Layout: SPV 
0.80.80.8vatalanibKDRKITFLT1

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+ vatalanibdown-regulates img/direct_inhibition.png chemical inhibition KDR 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-207645 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
+ vatalanibdown-regulates img/direct_inhibition.png chemical inhibition KIT 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-207648 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
+ vatalanibdown-regulates activity img/direct_inhibition.png chemical inhibition KDR 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258309 in vitro
pmid sentence
Our data set represents the most detailed comprehensive assessment of the reactivity of known and clinical kinase inhibitors across the kinome published to date. | The data also show that for at least 15 of the 27 kinases that are the primary, intended targets for the compounds tested and that are represented in the assay panel, selective inhibitors, as assessed by both absolute selectivity across the kinome and selectivity relative to the primary target, are among the 72 tested here.
Publications: 1 Organism: In Vitro
+ vatalanibdown-regulates img/direct_inhibition.png chemical inhibition FLT1 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-207642 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
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