| + |
AARS1 | down-regulates quantity 
chemical modification
|
alanine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270446 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32314272 |
Alanyl-tRNA synthetase 1 (AARS1) gene encodes a ubiquitously expressed class II enzyme that catalyzes the attachment of alanine to the cognate tRNA. AARS1 mutations are frequently responsible for autosomal dominant Charcot-Marie-Tooth disease type 2N (CMT2N). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
alanine | up-regulates quantity 
|
AminoAcids |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264746 |
|
|
|
|
| pmid |
sentence |
| 29259120 |
All extant life employs the same 20 amino acids for protein biosynthesis |
|
| Publications: |
1 |
| + |
SLC36A2 | up-regulates quantity
relocalization
|
alanine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264740 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12748860 |
Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.|The first member of the SLC36 family, present in both intracellular and plasma membranes, was identified independently as a lysosomal amino acid transporter (LYAAT1) responsible for the export of lysosomal proteolysis products into the cytosol and as a proton/amino acid transporter (PAT1) responsible for the absorption of amino acids in the gut. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC36A1 | up-regulates quantity
relocalization
|
alanine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264739 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12748860 |
Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.|The first member of the SLC36 family, present in both intracellular and plasma membranes, was identified independently as a lysosomal amino acid transporter (LYAAT1) responsible for the export of lysosomal proteolysis products into the cytosol and as a proton/amino acid transporter (PAT1) responsible for the absorption of amino acids in the gut. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
alanine | up-regulates quantity
precursor of
|
Ala-tRNA(Ala) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270452 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32314272 |
Alanyl-tRNA synthetase 1 (AARS1) gene encodes a ubiquitously expressed class II enzyme that catalyzes the attachment of alanine to the cognate tRNA. AARS1 mutations are frequently responsible for autosomal dominant Charcot-Marie-Tooth disease type 2N (CMT2N). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
alanine