| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260284 |
|
|
Homo sapiens |
CACO-2 Cell |
| pmid |
sentence |
| 32142651 |
Indeed, the clinically proven serine protease inhibitor camostat mesylate, which is active against TMPRSS2 (Kawase et al., 2012), partially blocked SARS-2-S-driven entry into Caco-2 (Figure S3 B) and Vero-TMPRSS2 cells (Figure 4 A). Full inhibition was attained when camostat mesylate and E-64d, an inhibitor of CatB/L, were added (Figure 4A; Figure S3B), indicating that SARS-2-S can use both CatB/L as well as TMPRSS2 for priming in these cell lines. |
|
3.0
Camostat
chemical inhibition