| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259903 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 14748653 |
Tositumomab is an immunoglobulin G murine monoclonal antibody that binds to the CD20 antigen on the surface of normal and malignant human B-cells. Tositumomab is linked covalently with iodine-131 to produce the radioimmunoconjugate iodine-131 tositumomab (Bexxar). The iodine-131 tositumomab regimen was approved by the US Food and Drug Administration in June 2003 for the treatment of patients with CD20-positive, follicular non-Hodgkin's lymphoma, both with and without transformation, whose disease is refractory to rituximab (Rituxan) and has relapsed following chemotherapy. |
|
3.0
tositumomab and iodine i 131 tositumomab
binding