| + |
ILK | up-regulates
phosphorylation
|
NACA |
0.428 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-127631 |
Ser1906 |
PELEEQDsTQATTQQ |
Homo sapiens |
|
| pmid |
sentence |
| 15299025 |
The inactivation of gsk3? In response to adhesion and ilk activation (6) would then result in a thr-159-hypophosphorylated ?-Nac that would become unavailable for proteasome degradation but would become a substrate for the ilk kinase activity on residue ser-43. The ser-43-phosphorylated ?-Nac would preferentially interact with c-jun (30), translocate to the nucleus, and potentiate transcription |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GSK3B | down-regulates
phosphorylation
|
NACA |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-123262 |
Thr2022 |
NIQENTQtPTVQEES |
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 15005626 |
Gsk3 beta-dependent phosphorylation of the alpha nac coactivator regulates its nuclear translocation and proteasome-mediated degradation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |