Summary

Name PSMD11
Full Name 26S proteasome non-ATPase regulatory subunit 11
Synonyms 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit S9, 26S proteasome regulatory subunit p44.5 |
Primary ID O00231
Links - -
Type protein
Relations 1
Function Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs)

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding 26S Proteasome 0.897
Publications: 1 Organism: Homo Sapiens