3.0
Summary
| Name |  FCHO1
|
| Full Name | F-BAR domain only protein 1 |
| Synonyms | FCHO1_HUMAN | KIAA0290 |
| Primary ID | O14526 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | FCHO1 | up-regulates quantity by stabilization 
binding
|
AP-2/clathrin vescicle | 0.499 |
| Publications: | 1 | |||