Summary

Name AP3D1
Full Name AP-3 complex subunit delta-1
Synonyms AP-3 complex subunit delta, Adaptor-related protein complex 3 subunit delta-1, Delta-adaptin |
Primary ID O14617
Links - -
Type protein
Relations 2
Function Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation (PubMed:26744459). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ AP3D1form complex img/form-complex.png binding Neuronal AP-3 0.809
Publications: 1 Organism: Homo Sapiens
+ AP3D1form complex img/form-complex.png binding AP-3 complex 0.931
Publications: 1 Organism: Homo Sapiens