Summary

Name EPHB6
Full Name Ephrin type-B receptor 6
Synonyms HEP, Tyrosine-protein kinase-defective receptor EPH-6 |
Primary ID O15197
Links - -
Type protein
Relations 2
Function Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. {ECO:0000269|PubMed:12517763, ECO:0000269|PubMed:15955811}.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding EPHA2 0.397
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding CBLC 0.276
Publications: 1 Organism: Homo Sapiens