| Name
|
 NKRF
|
| Full Name |
NF-kappa-B-repressing factor |
| Synonyms |
NFkB-repressing factor, Protein ITBA4, Transcription factor NRF | ITBA4, NRF |
| Primary ID |
O15226 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. |
4.0
transcriptional regulation