| Name
|
 GRIN2D
|
| Full Name |
Glutamate receptor ionotropic, NMDA 2D |
| Synonyms |
GluN2D, EB11, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, NMDAR2D, NR2D | GluN2D, NMDAR2D |
| Primary ID |
O15399 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750). |
3.0
binding