+ |
TFEB | up-regulates quantity by expression
transcriptional regulation
|
NDUFS4 |
0.248 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-276705 |
|
|
|
|
pmid |
sentence |
33176151 |
Genes responsive to high, sustained levels of nuclear TFEB induced by Torin treatment included CTSF, NPC2, BLOC1S3, and BLOC1S2, which function in lysosomal degradation, transport, and biogenesis; NDUFS4, NDUFA13, NDUFA8, NDUFA1, NDUFB10, and NDUFAF2, subunits of mitochondrial NADH dehydrogenase; PPARG and PPARGC1A, a nuclear receptor and co-factor regulating lipid metabolism; and BHLHE40 and BHLHE41, two transcriptional repressors (Figures 4B and 4D; Table S4). |
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Publications: |
1 |
+ |
NDUFS4 | form complex
binding
|
Mitochondrial respiratory chain complex I |
0.84 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262178 |
|
|
|
|
pmid |
sentence |
30030361 |
Thus, we now know the complete mammalian cI structure [22,23] and how the subunits are organized in six modules (N, Q, ND1, ND2, ND4 and ND5)The N-module, which is the tip of the hydrophilic arm and the last one to be incorporated [30,35], results from the assembly of NDUFV1, NDUFV2, NDUFS1 and NDUFA2 [34], to which NDUFA6, NDUFA7, NDUFA12, NDUFS4, NDUFS6 and NDUFV3 must be further associated with to complete the module [24]. |
|
Publications: |
1 |