Summary

Name TNFSF14
Full Name Tumor necrosis factor ligand superfamily member 14
Synonyms Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand | HVEML, LIGHT
Primary ID O43557
Links - -
Type protein
Relations 1
Function Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM (PubMed:9462508, PubMed:10754304). Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (PubMed:10754304).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding TNFRSF14 0.854
Publications: 1 Organism: Homo Sapiens
Tissue: Lung