| + |
NTRK2 | up-regulates activity 
phosphorylation
|
FRS3 |
0.584 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250202 |
Tyr417 |
EPPRQLNyIQVELKG |
Homo sapiens |
|
| pmid |
sentence |
| 11432792 |
The tyrosine phosphoryla tion of FRS2/SNT2 was stimulated dependently on the TrkB activation. to explore the possibility that tyrosine residues 417 and 455 on FRS2/SNT2 function as the binding sites for Shp2, we coexpressed Y417F or Y455F phenylalanine mutants and the Y417/455F double phenylalanine mutant of Myc/Histagged FRS2/SNT2 with TrkB. The active TrkB induced somewhat reduced tyrosine phosphorylation of all of the phenylalanine mutants of FRS2/SNT2 in comparison with tyrosine phosphorylation of the wild type |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250203 |
Tyr455 |
PARSSDSyAVIDLKK |
Homo sapiens |
|
| pmid |
sentence |
| 11432792 |
The tyrosine phosphoryla tion of FRS2/SNT2 was stimulated dependently on the TrkB activation. to explore the possibility that tyrosine residues 417 and 455 on FRS2/SNT2 function as the binding sites for Shp2, we coexpressed Y417F or Y455F phenylalanine mutants and the Y417/455F double phenylalanine mutant of Myc/Histagged FRS2/SNT2 with TrkB. The active TrkB induced somewhat reduced tyrosine phosphorylation of all of the phenylalanine mutants of FRS2/SNT2 in comparison with tyrosine phosphorylation of the wild type |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
3.0
FRS3
- 
- 