3.0
Summary
| Name |  DENR
|
| Full Name | Density-regulated protein |
| Synonyms | DRP, Protein DRP1, Smooth muscle cell-associated protein 3, SMAP-3 | DRP1 |
| Primary ID | O43583 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. |
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transcriptional regulation