Summary

Name PLRG1
Full Name Pleiotropic regulator 1
Synonyms PLRG1_HUMAN
Primary ID O43660
Links - -
Type protein
Relations 3
Function Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (PubMed:11101529, PubMed:11544257).

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Relations

Regulator Mechanism target score ℹ
+ PLRG1form complex img/form-complex.png binding PRP19-CDC5L 0.8
Publications: 1 Organism: Homo Sapiens
+ PLRG1up-regulates activity img/direct-activation.png binding HNRNPM 0.747
Publications: 1 Organism: Homo Sapiens
+ WEE1down-regulates activity img/direct_inhibition.png phosphorylation PLRG1 0.2
Publications: 1 Organism: Homo Sapiens