3.0
Summary
| Name |  SH3BP5View Modifications |
| Full Name | SH3 domain-binding protein 5 |
| Synonyms | SH3BP-5, SH3 domain-binding protein that preferentially associates with BTK | SAB, SAB |
| Primary ID | O60239 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed:26506309, PubMed:30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. |
phosphorylation