+ |
CAMK2G | down-regulates activity
phosphorylation
|
ADCY3 |
0.36 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-250691 |
Ser1076 |
NVASRMEsTGVMGNI |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
8798667 |
Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo. | Site-directed mutagenesis of a CaM kinase II consensus site (Ser-1076 to Ala-1076) in III-AC greatly reduced Ca2+-stimulated phosphorylation and inhibition of III-AC in vivo. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NF1 | up-regulates
|
ADCY3 |
0.267 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-204034 |
|
|
Homo sapiens |
|
pmid |
sentence |
24431436 |
Nf1encodes neurofibromin, a protein with multiple functions including ras inactivation (ras gtpase-activating protein or rasgap) and adenylyl cyclase (ac) activation |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ADCY3 | up-regulates quantity
chemical modification
|
3',5'-cyclic AMP |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265000 |
|
|
Homo sapiens |
|
pmid |
sentence |
15385642 |
Adenylyl cyclases (AC), a family of enzymes that catalyze the synthesis of cyclic AMP, are critical regulators of cellular functions. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |