Summary

Name CAMK2G
Full Name Calcium/calmodulin-dependent protein kinase type II subunit gamma
Synonyms CaM kinase II subunit gamma, CaMK-II subunit gamma | CAMK, CAMK-II, CAMKG
Primary ID Q13555
Links - -
Type protein
Relations 33
Function Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In the central nervous system, it is involved in the regulation of neurite formation and arborization (PubMed:30184290). It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

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Relations


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Regulator Mechanism target score ℹ
+ CAMK2Gdown-regulates activity img/direct_inhibition.png phosphorylation EGFR 0.354
Publications: 2 Organism: , Homo Sapiens
+ CAMK2Gdown-regulates activity img/direct_inhibition.png phosphorylation ADCY3 0.346
Publications: 1 Organism: Homo Sapiens
+ CAMK2Gdown-regulates activity img/direct_inhibition.png phosphorylation Adenylate_cyclase 0.542
Publications: 1 Organism: Homo Sapiens
+ CAMK2G