Summary

Name PLXNC1
Full Name Plexin-C1
Synonyms Virus-encoded semaphorin protein receptor | VESPR
Primary ID O60486
Links - -
Type protein
Relations 2
Function Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding PLXNC1 0.911
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination PLXNC1 0.2
Publications: 1 Organism: Homo Sapiens