Summary

Name PRMT3
Full Name Protein arginine N-methyltransferase 3
Synonyms EC 2.1.1.319, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3 | HRMT1L3
Primary ID O60678
Links - -
Type protein
Relations 1
Function Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (PubMed:33495566). {ECO:0000269|PubMed:33495566, ECO:0000305|PubMed:33495566}.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding ALDH1A1 0.2
Publications: 1 Organism: Homo Sapiens