| + |
EIF1B | up-regulates activity 
relocalization
|
40S cytosolic small ribosomal subunit |
0.472 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269145 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20921384 |
Genetic and biochemical studies have revealed several eukaryotic factors involved in selecting the correct initiation codon (3–6). Further analyses pointed toward eukaryotic initiation factor 1 (eIF1) as the key mediator of this process (7–10). eIF1 binds near the P-site of the small ribosomal subunit (11); this binding is thought to lead to an open conformation of the preinitiation complex favoring scanning |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
EIF1B | down-regulates activity 
|
60S cytosolic large ribosomal subunit |
0.255 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269146 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 14600024 |
Binding of eIF1 to the 40S subunit would block access of the 60S |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
EIF1B
- 
- 