Summary

Name RAMP1
Full Name Receptor activity-modifying protein 1
Synonyms Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1 |
Primary ID O60894
Links - -
Type protein
Relations 1
Function Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:33602864, PubMed:9620797, PubMed:35324283, PubMed:38603770). Required for the transport of CALCRL to the plasma membrane (PubMed:9620797). Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB (PubMed:33602864, PubMed:9620797). Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA (PubMed:35324283, PubMed:38603770).

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Relations

Regulator Mechanism target score ℹ
+ RAMP1form complex img/form-complex.png binding Amylin receptor 1 complex 0.753
Publications: 1 Organism: Homo Sapiens