| + |
KIF21B | up-regulates 
|
Plus-end directed sliding movement |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272515 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28290984 |
In this study, we showed that KIF21B is a highly processive MT plus-end directed motor, which can potently induce pausing of MT plus ends. This activity depends on several regions of this large motor protein. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TRIM31 | up-regulates activity 
binding
|
KIF21B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272479 |
|
|
|
|
| pmid |
sentence |
| 24086586 |
Here we show that the ubiquitin E3 ligase TRIM3, also known as BERP, interacts with KIF21B via its RBCC domain ||he E3-ligase function of TRIM3 is not involved in KIF21B degradation, however TRIM3 depletion reduces the motility of the motor. Together, our data suggest that TRIM3 is a regulator in the modulation of KIF21B motor function |
|
| Publications: |
1 |
3.0
KIF21B
- 
- 