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Summary
Name
DNAJC6
Full Name
Putative tyrosine-protein phosphatase auxilin
Synonyms
DnaJ homolog subfamily C member 6 | KIAA0473
Primary ID
O75061
Links
-
-
Type
protein
Relations
1
Function
Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons (By similarity).
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relocalization
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up-regulates activity
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Relations
Regulator
Mechanism
target
score
ℹ
+
DNAJC6
up-regulates activity
relocalization
HSPA8
0.879
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-260719
pmid
sentence
24789820
Hsc70, recruited by the J-domain protein auxilin, mediates clathrin uncoating and release of a free vesicle, primed to fuse with a target membrane.
Publications:
1