Summary

Name HIP1R
Full Name Huntingtin-interacting protein 1-related protein
Synonyms HIP1-related protein, Huntingtin-interacting protein 12, HIP-12 | HIP12, KIAA0655
Primary ID O75146
Links - -
Type protein
Relations 1
Function Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation HIP1R 0.299
Publications: 1 Organism: Homo Sapiens