3.0
Summary
| Name |  ADAMTS4View Modifications |
| Full Name | A disintegrin and metalloproteinase with thrombospondin motifs 4 |
| Synonyms | ADAM-TS 4, ADAM-TS4, ADAMTS-4, ADMP-1, Aggrecanase-1 | KIAA0688 |
| Primary ID | O75173 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. |
cleavage