Summary

Name RTN2
Full Name Reticulon-2
Synonyms Neuroendocrine-specific protein-like 1, NSP-like protein 1, Neuroendocrine-specific protein-like I, NSP-like protein I, NSPLI | NSPL1
Primary ID O75298
Links - -
Type protein
Relations 1
Function Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (PubMed:15286784). Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity). Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity). {ECO:0000250|UniProtKB:O70622, ECO:0000250|UniProtKB:Q6WN19, ECO:0000269|PubMed:15286784}.

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Relations

Regulator Mechanism target score
+ down-regulates quantity img/direct_inhibition.png ubiquitination RTN2 0.2
Publications: 1 Organism: Homo Sapiens