Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-195749 |
|
|
Homo sapiens |
|
pmid |
sentence |
22302992 |
Gpc4 bound to wnt3a and wnt5a which activate the beta-catenin-dependent and -independent pathways, respectively, and colocalized with wnts on the cell surface. Expression of gpc4 enhanced the wnt3a-dependent beta-catenin pathway and the wnt5a-dependent beta-catenin-independent pathway, and knockdown of gpc4 suppressed both pathways |
|