Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273832 |
Ser18 |
TPLHRRAsTPLPLSP |
Homo sapiens |
HeLa Cell |
pmid |
sentence |
22076634 |
We found that activation of protein kinase D1, a protein kinase downstream of α(1)-adrenergic signaling, leads to direct phosphorylation of Rem1 at Ser18. This results in an increase of the channel activity and plasma membrane expression observed by using a combination of electrophysiology, live cell confocal microscopy, and immunohistochemistry in heterologous expression system and neonatal cardiomyocytes. |
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