3.0
Summary
| Name |  SNRNP200
|
| Full Name | U5 small nuclear ribonucleoprotein 200 kDa helicase |
| Synonyms | Activating signal cointegrator 1 complex subunit 3-like 1, BRR2 homolog, U5 snRNP-specific 200 kDa protein, U5-200KD | ASCC3L1, HELIC2, KIAA0788 |
| Primary ID | O75643 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes (PubMed:28502770, PubMed:28781166, PubMed:29361316, PubMed:30315277, PubMed:29360106, PubMed:29301961, PubMed:30728453, PubMed:30705154). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SNRNP200 | form complex 
binding
|
U4/U6.U5 snRNP complex | 0.774 |
| Publications: | 1 | Organism: | Homo Sapiens | |