Summary

Name KLF7
Full Name Krueppel-like factor 7
Synonyms Ubiquitous krueppel-like factor | UKLF
Primary ID O75840
Links - -
Type protein
Relations 2
Function Transcriptional factor (PubMed:9774444, PubMed:16339272). Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation (PubMed:28916725). Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells (PubMed:16339272). Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin (PubMed:16339272).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding KLF7 0.595
Publications: 1 Organism: Chlorocebus Aethiops
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CDKN1A 0.274
Publications: 1 Organism: Chlorocebus Aethiops