Relation Results

Summary

Name NFASC
Full Name Neurofascin
Synonyms NFASC_HUMAN | KIAA0756
Primary ID O94856
Links - -
Type protein
Relations 3
Function Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell ...
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Type: Score: Layout: SPV 
0.7440.6920.683NFASCANK3ANK2ANK1

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Relations
Regulator
Mechanism
target
score ℹ
+ NFASCup-regulates quantity img/direct-activation.png relocalization ANK3 0.744
Identifier Residue Sequence Organism Cell Line
SIGNOR-266717 Rattus norvegicus
pmid sentence
Neurofascin, L1, NrCAM, NgCAM, and neuroglian are membrane-spanning cell adhesion molecules with conserved cytoplasmic domains that are believed to play important roles in development of the nervous system. This report presents biochemical evidence that the cytoplasmic domains of these molecules associate directly with ankyrins, a family of spectrin-binding proteins located on the cytoplasmic surface of specialized plasma membrane domains.
Publications: 1 Organism: Rattus Norvegicus
Tissue: Central Nervous System
+ NFASCup-regulates quantity img/direct-activation.png relocalization ANK2 0.692
Identifier Residue Sequence Organism Cell Line
SIGNOR-266716 Rattus norvegicus
pmid sentence
Neurofascin, L1, NrCAM, NgCAM, and neuroglian are membrane-spanning cell adhesion molecules with conserved cytoplasmic domains that are believed to play important roles in development of the nervous system. This report presents biochemical evidence that the cytoplasmic domains of these molecules associate directly with ankyrins, a family of spectrin-binding proteins located on the cytoplasmic surface of specialized plasma membrane domains.
Publications: 1 Organism: Rattus Norvegicus
Tissue: Central Nervous System
+ NFASCup-regulates quantity img/direct-activation.png relocalization ANK1 0.683
Identifier Residue Sequence Organism Cell Line
SIGNOR-266718 Rattus norvegicus
pmid sentence
Neurofascin, L1, NrCAM, NgCAM, and neuroglian are membrane-spanning cell adhesion molecules with conserved cytoplasmic domains that are believed to play important roles in development of the nervous system. This report presents biochemical evidence that the cytoplasmic domains of these molecules associate directly with ankyrins, a family of spectrin-binding proteins located on the cytoplasmic surface of specialized plasma membrane domains.
Publications: 1 Organism: Rattus Norvegicus
Tissue: Central Nervous System
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