| Name
|
 FARP2
|
| Full Name |
FERM, ARHGEF and pleckstrin domain-containing protein 2 |
| Synonyms |
FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3 | KIAA0793, PLEKHC3 |
| Primary ID |
O94887 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). |
3.0
transcriptional regulation