Summary

Name RHOBTB3
Full Name Rho-related BTB domain-containing protein 3
Synonyms EC 3.6.1.- | KIAA0878
Primary ID O94955
Links - -
Type protein
Relations 2
Function Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9. {ECO:0000269|PubMed:19490898}.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png binding CCNE1 0.417
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding Cullin 3-RBX1-Skp1 0.392
Publications: 1 Organism: Homo Sapiens