| + |
UPP2 | down-regulates quantity 
chemical modification
|
uracil |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280537 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280529 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
UPP2 | down-regulates quantity
chemical modification
|
2-deoxy-D-ribofuranose 1-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280538 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UPP2 | down-regulates quantity
chemical modification
|
alpha-D-ribose 1-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280530 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UPP2 | up-regulates quantity 
chemical modification
|
uridine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280531 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UPP2 | up-regulates quantity
chemical modification
|
2'-deoxyuridine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280539 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
UPP2
- 
- 