| + |
KCNB1 | up-regulates quantity 
relocalization
|
VAPB |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262121 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 29941597 |
Confirmation that Kv2.1 and -2.2 bind VAPA and VAPB employed colocalization/redistribution, siRNA knockdown, and Förster resonance energy transfer (FRET)-based assays.|As Kv2.1 accumulates on the surface it begins to bind ER VAPs and form the large and stable membrane junctions. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
VAPB | form complex 
binding
|
VAPB-PTPIP51 complex |
0.606 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262118 |
|
|
Rattus norvegicus |
|
| pmid |
sentence |
| 30841933 |
Here, we demonstrate that the VAPB-PTPIP51 tethers regulate synaptic activity. VAPB and PTPIP51 localise and form contacts at synapses, and stimulating neuronal activity increases ER-mitochondria contacts and the VAPB-PTPIP51 interaction. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| Tissue: |
Brain |
| + |
KCNB2 | up-regulates quantity
relocalization
|
VAPB |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262123 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 29941597 |
Confirmation that Kv2.1 and -2.2 bind VAPA and VAPB employed colocalization/redistribution, siRNA knockdown, and Förster resonance energy transfer (FRET)-based assays.|As Kv2.1 accumulates on the surface it begins to bind ER VAPs and form the large and stable membrane junctions. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
VAPB
- 
- 