Summary

Name FARS2
Full Name Phenylalanine--tRNA ligase, mitochondrial
Synonyms Phenylalanyl-tRNA synthetase, PheRS | FARS1
Primary ID O95363
Links - -
Type protein
Relations 1
Function Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation FARS2 0.2
Publications: 1 Organism: Homo Sapiens